
PhD Work in progress
WIP 2025

- studiare
8 SETTEMBRE
9:30 Welcome
SESSION 1
CHAIR - Michela A. Denti & Alessandro Romanel
09:50 Laura Bartolomei
Overcoming radio-resistance by targeting p21 in colorectal cancer
10:10 Irene Pecchini
Telomere maintenance mechanisms engage RNA sensing to shape the immune landscape in brain tumors
10:30 Daniele Migliorati
Harnessing Multiplexed Base Editing Screens for Targeted Functional Genomics
10:50 Giulia Vitali
Dissecting the role of RNA in the fine tuning of MLL4 function
COFFEE BREAK
SESSION 2
CHAIR - Massimo Pizzato & Paolo Macchi
11:30 Vittorio Bontempi
Heterogeneity of Telomere Maintenance Mechanisms in Diffuse Gliomas at the Single Cell Level
11:50 Alessia Marinelli
In vitro evidence of TME cell reprogramming by prostate cancer-derived large extracellular vesicles
12:10 Cosimo Sabino
Rapamycin deregulated genes as new potential targets for antiaging interventions
12:30 Giorgia Pellizzaro
METTL3 inhibition primes AML cells to STING-driven mitochondrial apoptosis
LUNCH TIME
14:00 - 16:00 POSTER SESSION
SESSION 3
CHAIR - Alberto Inga & Maria Caterina Mione
15:50 Dalila Paladino
Modulating HuR activity as a novel anti-psoriatic pharmacological strategy
16:10 Christian Ramirez Amarilla
Dissecting the Role of the m6A Complex in Leukemia via Multiomic Profiling
16:30 Federica Busi
A message from melanoma: EVs as drivers of RLRs-mediated inflammation
16:50 Paolo Brunelli
OptoTrkB neural activation for in vivo translation of optogenetic memory engram consolidation
17:10 Laura Alunno
How a 3'UTR tranSNP controls DDIT4 protein output
9 SETTEMBRE
SESSION 4
CHAIR - Martin M. Hanczyc & Orietta Massidda
09:30 Giorgia Zappacosta
Friedreich's Ataxia: increase the expression of frataxin by genome editing
09:50 Anna Barbieri
MYC-Driven Gliosis Impairs Neuronal Survival and Contributes to Early Senescence in Amyotrophic Lateral Sclerosis
10:10 Matteo Ciciani
Systematic investigation of the diversity of prokaryotic mobile genetic elements using massive metagenomic and metatranscriptomic data
10:30 Elena Cerri
Disrupting m6A–YTHDF protein interactions to unlock new therapeutic strategies in AML
COFFEE BREAK
11:00 - 15:30 POSTER SESSION
SESSION 5
CHAIR - Marta Biagioli & Nicola Segata
15:30 Rebecca Binacchi
ETV7 as a novel potential target to address cancer aggressiveness and chemoresistance
15:50Gian Mario Moretta
m6A writer complex: epitranscriptomic regulator of p53 pathway
16:10 Lucia Santomaso
Dissecting the role of MLL4 in Kabuki syndrome pathogenesis through the lenses of cell differentiation
16:30 Marta Stancampiano
Targeting the lung epithelium for advanced therapies in cystic fibrosis
16:50 Ilaria Bruno
RiboWich: high-throughput ribosome profiling for enabling beyond generation studies of translation
17:10 Final Meeting
MEETING WITH THE DIRECTOR AND THE VICE COORDINATOR OF THE PHD
18:30 MUSIC & APERITIV
Progetto MEDAGLIA LIVE MUSIC